Background: Hypophosphatasia (HPP) is a rare inborn error of metabolism that results from a dysfunctional tissue non-specific alkaline phosphatase enzyme (TNSALP).Although genotype-phenotype correlations have been described in HPP patients, only sparse information is currently available on the genetics of mild type HPP.Methods: We investigated 5 Ja
Among the aspects that are often used as indicators of welfare measure are income, population, health, education, employment, consumption, housing, and social culture.If we use indicators will arise the question of whether the fulfillment of the indicators that a person would have to obtain welfare, why some people already have the luxury homes, ve
The global burden of non-communicable diseases (NCDs) has been rising.A key risk factor for NCDs is obesity, which has been partly linked to consumption of sugar sweetened beverages (SSBs).A tax on SSBs is an attractive control measure to curb the rising trend in NCDs, as it has the potential to reduce consumption of SSBs.However, studies on the po
Histone methylation Wire Shelving regulates normal stem cell fate decisions through a coordinated interplay between histone methyltransferases and demethylases at lineage specific genes.Malignant transformation is associated with aberrant accumulation of repressive histone modifications, such as polycomb mediated histone 3 lysine 27 (H3K27me3) resu